Immunization 101: Pentavalent (5-in-1) Vaccine

Last week, our little Queen B had two vaccinations schedule. The first one was last October 26 for the second dosage of her Influenza vaccine (more commonly known as the flu vaccine) at our pediatrician while the second was last October 28 for a dosage of the Measles vaccine at the local health center. So far, Georgina had already a total of 13 injections. It could have been much more if not for the development of combination vaccines.

A combination vaccine is a vaccine that contains immunizing antigen against more than one vaccine preventable disease. According to www.vaccine-safety-training.org , here are the potential benefits of combination vaccines:


  • It reduces the cost of stocking and administering of separate vaccines.
  • It reduces the cost of extra health care visits.
  • It improves the timeliness of vaccination as some parents and health care providers object to administering more than two or three injectable vaccines during a single visit because of child’s fear of needles and pain, and because of concerns regarding safety.
  • It facilitates the addition of new vaccines into immunization programs.

An example of a combination vaccine is the Pentavalent Vaccine, also called 5-in-1 vaccine, which combines vaccines against Diphtheria, Tetanus, Pertussis (whooping cough), Hepatitis B, and Haemophilus influenza type B in one preparation.

Diphtheria
It is a serious infection caused by the bacterium Corynebacterium diphtheria. Its signs and symptoms include a thick, gray membrane covering one’s throat and tonsils, sore throat and hoarseness, swollen glands in the neck, difficulty in breathing, nasal discharge, fever, and chills. This disease can be fatal especially for children under five years old.

Tetanus
It is an infection caused by the bacterium Clostridium tetani which is commonly found in soil, dust, and manure. The bacteria can enter the body through a break in the skin such as a cut or a puncture wound by a contaminated object. This disease is commonly called lockjaw as spasms and stiffness in the jaw muscles is its first symptom. Other symptoms (in order of appearance) include stiffness of the neck muscles, difficulty in swallowing, stiffness of the abdominal muscles, and painful body spasms lasting for several minutes which can be triggered by a draft, a loud noise, a physical touch, or even light. Fever, sweating, elevated blood pressure, and rapid heart rate are other signs and symptoms of this disease. Since tetanus can interfere with one’s breathing, it is a life threatening disease.

Neonatal tetanus is a form of generalised tetanus that occurs in newborns. Since I had my booster shot of the tetanus vaccine just two or three years (it is effective for 10 years) before I got pregnant, my little Queen B was able to acquire passive immunity against it.

Pertussis
It is a highly contagious disease caused by the bacterium Bordetella pertussis. Initial symptoms resemble the common cold which include runny nose, nasal congestion, red, watery eyes, fever, and cough. After a week or two, the symptoms will get worse. The severe coughing may cause vomiting and extreme fatigue. Infants may not cough at all but have periods where they do not breathe instead. It is an airborne illness that spreads through the coughs and sneezes of the infected person.


Haemophilus influenza type B (Hib)

The Haemophilus influenza type B bacteria may cause several life-threatening diseases such as meningitis which affects the brain, epiglottitis which affects the throat and can cause death by suffocation, pericarditis which affects the heart, pneumonia which affects the lungs, and septic arthritis which affects the bones and joints. .

I have already discussed Hepatitis B in here.

The Pentavalent Vaccine is part of the Philippine Expanded Program of Immunization so it should be available at our local health centers. Three (3) dosages of the Pentavalent Vaccine are needed. The first dose can be given as early as six (6) weeks of age with four (4) weeks interval between dosages. Our little Queen B received her final shot of the Pentavalent Vaccine last June 17. All dosages of the Pentavalent Vaccine are given intramuscularly.

Additional dosages of vaccines are needed for Diphtheria, Tetanus, Pertussis (whooping cough), and Haemophilus influenza type B bacteria. For Diphtheria, Tetanus, and Pertussis (DTP), two (2) additional shots should be received. The fourth dose can be given as early as twelve (12) months of age provided there is an interval of at least six (6) months from the third dose while the fifth dose can be given as early as four (4) years of age. If the fourth dose was administered at age 4 years or older, a fifth dose may not be given. As for Haemophilus influenza type B (Hib) bacteria, a booster dose should be administered between 12-15 months of age with an interval of at least six (6) months from the third shot. All additional dosages for DTP and Hib are no longer covered by the Philippine Expanded Program of Immunization so it can be availed at your trusted pediatrician.

We were fortunate that in our local health center, the Pentavalent Vaccine was always available during our little Queen B’s vaccination schedule. Sadly, this is not always the case elsewhere. It is important our babies do not miss a vaccination schedule because researchers have found that skipping vaccines puts your child at increased risk for contracting the disease. If a series of four (4) shots are recommended for a certain vaccine, please make sure that your child receives all the needed dosages.

Various studies have shown that combination vaccines such as the Pentavalent Vaccine are just as safe and effective when given individually. Even though I know by experience that the pain of a vaccine is only momentary, I would still not want to subject my baby to several shots in one given day. As it is, I am very careful with my words before and after every vaccination as I do not want Georgina to acquire a fear of injections or doctors. I hope that my words reassure her that the pain she will feel is nothing compared to the pain of the serious diseases the vaccine aims to protect her from. As always, clean surroundings, adequate sleep, exercise, and a healthy diet go a long way in protecting our children.

 #xoxo

Sources:
What to Expect the First Year

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